Wenger v McClaren, a weakened Arsenal squad (Flamini, Hleb and Silva gone, Fabregas, Toure, Senderos, Diaby, Nasri injured, Eduardo and Rosicky still in recovery) vs a Dutch side itching to capitalise on their under-dog status.
Arsenal still have the quality to deal with FC Twente but it will be a big test for the remaining first-teamers not to mention the young guns like Ramsey who'll be expected to step straight into action.
Predictions? I don't think Arsenal will get less than a draw here.

